Dr. Kanchan Chakma Profile

Curriculum Vitae of Professor Dr. Kanchan Chakma

University of Chittagong, Chittagong-4331 (Bangladesh)

WORK EXPERIENCE

Professor of Biochemistry and Molecular Biology

University of Chittagong [ Sep  2021  – Current ]

Associate Professor of Biochemistry and Molecular Biology

University of Chittagong [ Aug  2017  – Sep  2021  ]

Assistant Professor of Biochemistry and Molecular Biology

University of Chittagong [ May 2012 – Aug 2017 ]

Lecturer of Biochemistry and Molecular Biology

University of Chittagong [ Apr 2011 – May 2012 ]

Scientic Ocer of Tissue Banking and Biomaterial Research Unit

Bangladesh Atomic  Energy  Commission [ Oct 2006 – Apr 2011 ]

City: Dhaka

Scientic Ocer of Biochemistry Laboratory

Bangladesh Institute of Research and  Rehabilitation in Diabetes, Endocrine & Metabolic

Disorders [

Jul 2006 – Oct 2006 ]

City: Dhaka

Scientic Ocer of Divisional DNA Screening Laboratory

Ministry of Women  and Children Aairs-Bangladesh [ May 2006 – Jul 2006 ]

City: Dhaka

Biochemist

Popular Diagnostic Centre  [ Mar 2005 – Apr 2006 ]

City: Dhaka

Country: Bangladesh

Doctor of Philosophy (Ph.D.) in Medical Science

Tohoku  University [ Apr 2012 – Mar 2016 ]

Address: 980-8577 Sendai (Japan) http://www.tohoku.ac.jp/en/ Field(s) of study: Medical Science

Thesis: IRX4  plays  an important role in pancreatic carcinogenesis

Researcher (Cancer Biology)

Institute of Development, Aging,  and Cancer  (IDAC),  Tohoku  University [ 1 Sep 2011 – 31 Mar 2012 ]

Address: 4-1 Seiryocho,  Aobaku,  980-8575  Sendai (Japan)

http://www.idac.tohoku.ac.jp/site/

Researcher (Analysis of protein structure and function) Ibaraki University [ 20 Oct 2008  – 23 Jan 2009  ] Address: Mito (Japan)

https://www.ibaraki.ac.jp/en/

Spectroscopic and biochemical analyses of protein structure and function.

Scientic Ocer (Basic Orientation Course for Scientists)

Bangladesh Atomic  Energy  Commission [ 28 May 2008 – 27 Aug 2008 ]

Address: Dhaka (Bangladesh) Final  grade : A+

Basic  Nuclear Orientation Course designed for newly  appointed scientists

Master of Science (M.Sc.) in Biochemistry & Molecular Biology (First Class)

University of Chittagong [ 2000]

Address: 4331 Chittagong (Bangladesh)

Field(s) of study: Biochemistry and Molecular Biology

Final grade : First Class (Equivalent to Grade ‘A’) [on a scale of A (best) to C (worst) in our academic  system]

Thesis: Identification of risk factors for the development of diabetes  mellitus in the population  of CTG

Bachelor of Science (B.Sc.) Honours in Biochemistry (First Class)

University of Chittagong [1999] Address: 4331 Chittagong (Bangladesh) Field(s) of study: Biochemistry

Final grade : First Class (Equivalent to Grade ‘A’) [on a scale of A (best) to C (worst) in our academic  system]

Higher Secondary Certicate (H.S.C.) in Science (First Division)

Rangamati Government College  (Chittagong Education Board)  [1996]

Secondary School Certicate (S.S.C.) in General Science (First Division)

Bandarban Government High School  (Comilla Education Board)  [1994]

AACR Global Scholar-in-Training Award

American Association for Cancer Research (AACR) [ 30 Mar  2019  ]

Japanese Government (Monbukagakusho: MEXT) Scholarship

Japanese  Government (Tohoku  University,  Japan) [ 2011 ]

MEXT Fellowship/The Nuclear Researchers Exchange Program

MEXT and Nuclear Safety Research Association (NSRA) | Ibaraki University (JAPAN) [ 2008  ]

NETWORKS AND  MEMBERSHIPS 

American Association for Cancer Research (AACR)

[ Philadelphia (PA),  USA,  1 Jan 2013  – Current ]

American Association for Cancer Education (AACE)

[ Charlottesville, VA 22911 USA, 1 Jan 2016 – 31 Dec 2016 ]

Cancer Epigenetics Society (CES)

[ Vienna, Austria, 2017  – Current ]

Bangladesh Society for Biochemistry and Molecular Biology (BSBMB)

[ Dhaka, Bangladesh, 2009  – Current ]

Graduate Biochemists Association (GBA), Bangladesh

[ Dhaka, Bangladesh, 2005  – Current ]

Bangladesh Bioethics Society (BBS)

[ Dhaka, Bangladesh, 2008  – Current ]

Tissue Banking Association of Bangladesh (TBAB)

[ Dhaka, Bangladesh, 2009  – Current ]

Bangladesh Biosafety and Biosecurity Association (BBBA)

[ Dhaka, Bangladesh, 2011  – Current ]

MANAGEMENT AND LEADERSHIP  SKILLS

Provost

Worked as Provost (Acting), Shah  Amanat Hall,  University of Chittagong from  July  2020  to August 2020.

Senior House Tutor

Worked as Senior House Tutor  at Shah  Amanat Hall,  University of Chittagong from  January 2019  to

January 2021.

Treasurer (2009-2011)

Tissue Banking Association of Bangladesh (TBAB)

Tohoku University International Medical Society (TUIMS)

Competent Leader (CL) (2016)

Achieved Competent Leader (CL)  award from  Toastmaster International, USA

COMMUNICATION AND INTERPERSONAL SKILLS 

Competent Communicator (CC) (2016)

Achieved Competent Communicator (CC)  award from  Toastmaster International, USA

PUBLICATIONS

A systemic analysis reveals TRIM24-SMARCC1 dependent poor prognosis of hepatocellular carcinoma.

[2020]

https://doi.org/10.1016/j.imu.2020.100467

Alam MM*, Chakma  K*, Hossain  MN, Ahsan T, Mahmud  S (* co-first author).

Informatics in Medicine Unlocked, 2020;  21:100467

Epigenetic inactivation of IRX4 is responsible for acceleration of cell growth in human pancreatic cancer.

[2020]

https://onlinelibrary.wiley.com/doi/10.1111/cas.14644

Chakma K, Gu Z, Abudurexiti Y, Hata  T, Motoi  F, Unno  M, Horii  A, Fukushige S

Cancer Science, 2020;  111:4594–4604

Methylation-mediated silencing of the LIM homeobox 6 (LHX6) gene promotes cell proliferation in human pancreatic cancer.

[2020]

https://doi.org/10.1016/j.bbrc.2020.03.120

Abudurexiti Y, Gu Z, Chakma K, Hata  T, Motoi  F, Unno  M, Horii  A, Fukushige S

Biochemical and  Biophysical Research Communications, 2020;  526(3):626-632

Nutritional Analysis and Phytochemical Evaluation of Bitter Gourd from Bangladesh

[2020]

https://doi.org/10.24203/ajafs.v8i2.6094

Barua R, Talukder MEU,  Islam  MS, Yesmin F, Chakma K, Kabir  MG, Bhuiyan RH Asian  Journal of Agriculture and Food  Sciences, 2020;  8(2):

11-17

Phylogenetic analysis and forensic evaluation among Rakhine, Marma, Hajong, and Manipuri tribes from four culturally dened regions of Bangladesh using 17 Y-chromosomal STRs. [2018]

https://doi.org/10.1007/s00414-018-1915-4

Hasan M, Sufian A, Momtaz P, Mazumder AK, Khondaker JA, Bhattacharjee S, Chakma K, Akhteruzz aman  S.

International Journal  of Legal Medicine, 2018;132(6):1641-1644

Islam  MZ,  Aklima J, Yesmin F, Islam  MS,  Chakma K, Alauddin M, Bhuiyan RH

International Journal of Contemporary Pediatrics, 2017;  4 (6)

Knowledge Levels and Life Style Practices for Cancer Prevention among Bangladeshi People

[2016]

https://doi.org/10.9734/BJMMR/2016/29306

Chakma K, Roy  CN

British Journal of Medicine & Medical Research, 2016; 18 (3):1-9

Antioxidant and Cytotoxic activity of Crude Flavonoid fraction from the fruits of hybrid variety of

Momordica charantia (Bitter Gourd).

[2014]

https://doi.org/10.9734/BJPR/2014/7288

Barua R, Samsad Sultana, Talukder MEU,  Chakma K, Hasan CMM, Islam  MS British Journal of Pharmaceutical Research, 2014;  4(7):

778-786

Bacterial contamination of the human amniotic membrane and bone tissue allograft.

[2012]

Hasan MZ,  Zohra FT, Bari SS, Miah  M, Chakma K, Nessa A, Parvez MAK  and Rahman MH.

Bangladesh Journal  of Medical  Sciences (BJMS),  2012; 18(1): 34-38

Ethical Perception of Tissue Banking in Bangladesh.

[2010]

https://doi.org/10.3329/bioethics.v1i2.9624

Zahid MZ, Chakma  K, Miah M and Nessa A.

Bangladesh Journal of Bioethics, 2010; 1(2):

11-19

Risk factors for developing Diabetes Mellitus amongst diabetic patients attending at the Chittagong

Diabetes Hospital Complex.

[2009]

https://doi.org/10.3329/bjnut.v22i0.12829

Chakma K, Banik  GR and Sikdar D.

Bangladesh Journal of Nutrition, 2009-10; 22-23: 31-40

Traditional knowledge related to medicinal and aromatic plants in tribal societies and the quantitative study of alkaloids in medicinal plants of the hill tracts in Bangladesh

[2008]

Chowdhury Z, Alamgir ANM,  Alauddin M, Islam  MS, Chakma K, Hoque MR, Kabir  MG Pharmacognosy Magazine (India), 2008;  4(15)  (Suppl): S137-S144

Chakraborty SK, Hasan MZ, Chakma K, Harun-Or-Rashid, Nessa A and Gomes DJ.

Dhaka University Journal of Biological Sciences, 2007; 16(2): 109-115

Dyslipidemia in Chakma Type 2 Diabetic Subjects of Bangladesh.

[2006]

https://chakmakc.fi  les.wordpress.com/2019/07/5.pdf

Hoque MR,  Chakma K, and Sikdar D.

Chittagong University Journal of Biological Sciences, 2006; 1(1): 49-55

Dyslipidemia in Type II Diabetes and the eect of Glycaemic control on Type II Diabetes

[2006]

https://chakmakc.fi  les.wordpress.com/2019/07/6.pdf

Banik GR, Islam MM, Zafar MA, and Chakma  K.

Hamdard Medicus (Pakistan), 2006; 49(4): 55-62.

BOOK  CHAPTER

Cancer Prevention and Control in Bangladesh: Mass Awareness is Needed.

[ 2020 ]

Chakma K, Roy  CN,  Das  AK, Hoque MA and  Sarkar AK. New  Insights into Disease and  Pathogen

Research, 2020;  Vol.  5: 1-12,  Book  Publisher International, India-UK.

https://doi.org/10.9734/bpi/nidpr/v5

CONFERENCES AND  SEMINAR

American Association for Cancer Research (AACR) Annual Meeting 2019

[ Atlanta,  GA, USA, 29 Mar 2019 – 3 Apr 2019 ]

Kanchan Chakma, Zhaodi Gu, Tatsuo Hata, Fuyuhiko Motoi, Michiaki Unno, Akira Horii, Shinichi Fukushige. DNA

hypermethylation of IRX4  is a frequent event  that may confer growth advantage to pancreatic cancer cells

International Cancer Education Conference 2016

[ Bethesda,  Maryland,  USA, 14 Sep 2016 – 16 Sep 2016 ]

Kanchan Chakma, Irona Khandakar and Chandra Nath Roy. A comprehensive cancer education program is urgently needed to reduce the cancer burden in Bangladesh

American Association for Cancer Research (AACR) Annual Meeting 2016

[ New  Orleans, LA. Philadelphia (PA),  USA,  16 Apr 2016  – 20 Apr 2016  ]

Shinichi Fukushige, Yasuhiko Mizuguchi, Kanchan Chakma, Yuriko Saiki, Akira Horii. Targeted TET

oxidase activity through methyl-CpG binding domain extensively suppresses cancer cell proliferation.

6th Retreat Conference of Tohoku University Graduate School of Medicine 2013

[ Sendai,  Japan, 2013 ]

KanchanChakma, Masanobu Satake, Shuntaro Ikawa. Role of p51/p63 in the regulation of keratinocyte proliferation and differentiation

J-Global Conference 2009

[ Japan, 2009 ]

Yuko Nihei,  Yuji Obara, CHAKMA Kanchan, Koyu Fujita , BROWN E. Doreen, DOOLEY M. David, Takamitsu Kohzuma. Spectroscopic and Electrochemical Properties of Pseudoazurin M16N and M16Q Mutant Proteins.

TECHNICAL SKILLS AND  COMPETENCES: 

Hands-On experiences in techniques:

Mammalian Cell Culture, Gel Electrophoresis, PCR,  Methyl Specific PCR  (MSP), DNA  extraction, DNA Sequencing, Bisulfite Sequencing, Protein isolation and purification, RNA isolation and purification, Western Blotting, RT-PCR, qPCR, Primer & Vector designing, Gene  Cloning (transformation, screening and transfection), construction of recombinant plasmid, plasmid DNA  isolation and purification,

genomic DNA  isolation and purification, recombinant plasmid construction from  genomic DNA, Quantification of DNA,  protein & RNA,  Colorimetry, Fluorescent microscopy, confocal microscopy, immunohistochemistry, MTT  assay, vector construction and purification of recombinant proteins

(FLAG-tagged), Ultra-centrifugation, Colony Formation Assay, Cell  Proliferation Assay, Scratch Assay, Invasion assay, Crystal Violet  Staining, Bacterial Cell Culture, Molecular Cloning, Transfection, Calf Intestinal Alkaline Phosphatase Assay (CIP), Stable Cell line Establishment, LacZ  Assay, Southern blotting using  a probe  labeled with radioisotope, Primer designing, iPS Cell Culture and maintenance.

Bioinformatics & computer experiences:

NCBI  database, PubMed database, SNP  database, cBioPortal database, TCGA database, CCLE database, COSMIC database, ENCODE database, Gene  Cards database, UniProt, Genetyx software, UCSC genome browser database, Genescript restriction enzyme site,  NEBCutter V2.0,  NIH  ImageJ, Fast  PCR,  SPSS, BLAST, Primer 3, MS-word, MS-  Excel, Power point,  Photoshop.

ORGANISATIONAL  SKILLS

Tissue Banking Association of Bangladesh (TBAB)

Treasurer (2009-2011)

Tohoku University International Medical Society (TUIMS)

Vice-President from  October 2012  to March 2016

OTHER COURSES AND TRAINING

Online courses:

◦  PH125.1x: Data Science: R Basics(MOOC) course offered by Harvard University, USA

◦  Introduction to R (MOOC) course offered by DataCamp.

◦  Introduction to Bioethics (MOOC) course offered by Georgetown University, USA

◦  Python Basics for Data Science course offered by International Business Machines Corporation

(IBM), USA

Generation and maintenance of human Induced Pluripotent Stem (iPS) cells

[ 29 Oct 2014 – 31 Oct 2014 ]

Training was  organized by Center for iPS Cell Research and  Application (CiRA), Kyoto  University, Japan.

I hereby declare that the above statements are correct and complete to the best of my knowledge. Sincerely

Kanchan Chakma